factor xiii
Definition
Noun: 1. A clotting factor: A substance in blood plasma that is essential for the final stage of blood clot formation. It is activated by thrombin and works to strengthen and stabilize a fibrin clot.
Usage
- Factor XIII is a specific protein (a clotting factor) in the blood.
- A deficiency in Factor XIII can lead to a serious bleeding disorder.
- Thrombin catalyzes the conversion of Factor XIII into its active enzyme form.
Examples
- The doctor ordered a test to measure the patient's Factor XIII levels.
- Factor XIII deficiency is a rare but severe condition.
- In the coagulation cascade, Factor XIII acts after fibrin has been formed.
Advanced Usage
- Activated Factor XIII (Factor XIIIa): The enzymatically active form of the protein, also known as or . It creates covalent bonds between fibrin strands.
- The active form, Factor XIIIa, cross-links the fibrin polymer to form a stable clot.
Variants and Related Words
- Fibrin-stabilizing factor: Another name for Factor XIII, describing its function.
- Fibrinase: An older term for the activated form (Factor XIIIa).
- Coagulation factor: The general category to which Factor XIII belongs.
Synonyms
- Fibrin-stabilizing factor
- (When activated): Fibrinase
Notes
- Factor XIII is often written with Roman numerals. It is one of the thirteen essential coagulation factors (I through XIII).
- Its primary role is not to initiate clotting but to stabilize the clot, preventing premature breakdown.
Noun
-
in the clotting of blood thrombin catalyzes factor XIII into its active form (fibrinase) which causes fibrin to form a stable clot
Khám phá thêm
Các từ liên quan
Từ đồng nghĩa
Từ gần giống
